An Economic and Relationship-strengthening Intervention to Reduce Alcohol Use in Malawi
Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Apr 10, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial, called Mlambe, is studying a program designed to help married couples in Malawi who are affected by HIV and have issues with alcohol use. The program focuses on improving financial skills and relationship communication to reduce heavy drinking and break the cycle of poverty that can lead to alcohol abuse. Researchers want to see if this approach is effective and cost-efficient in helping couples support each other better while managing their health.
To participate in the trial, couples must be married or living together, with at least one partner showing signs of problem drinking in the past three months and currently receiving treatment for HIV. It's important that both partners are open about their HIV status with each other. Couples dealing with serious issues like violence or those who took part in an earlier study will not be included. If eligible, participants can expect to engage in activities focused on saving money, learning about finances, and enhancing their relationship skills, all aimed at reducing alcohol use and improving their overall well-being.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. In a married or cohabitating union
- • 2. Have at least one partner with a positive AUDIT-C screen in prior 3 months
- • 3. Must also currently be on ART for at least 6 months
- • 4. Must have disclosed their HIV status to their partner
- Exclusion Criteria:
- • 1) Severe intimate partner violence reported in previous 3 months and/or fear that safety would be at risk by participation in the study (reported at screening). Couples who participated in Mlambe's pilot study will also be excluded.
About University Of California, San Francisco
The University of California, San Francisco (UCSF) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into effective therapies, UCSF collaborates with a diverse array of stakeholders, including healthcare professionals, industry partners, and patient communities. The university's research programs emphasize interdisciplinary approaches and leverage cutting-edge technology to address complex medical challenges. As a sponsor of clinical trials, UCSF is dedicated to maintaining the highest standards of ethical conduct and scientific rigor, ensuring the safety and well-being of participants while contributing to the broader medical knowledge base.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Zomba, , Malawi
Patients applied
Trial Officials
Amy Conroy, PhD
Principal Investigator
University of California, San Francisco
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported