Letrozole Alone Protocol Versus Using Letrozole and HCG Protocol
Launched by EGYMEDICALPEDIA · Apr 11, 2024
Trial Information
Current as of July 21, 2025
Completed
Keywords
ClinConnect Summary
The first pilot study for the clinical use of letrozole for ovarian induction in polycystic ovary syndrome (PCOS) patients was done in 2000.
In large randomized study, letrozole was superior to clomiphene as a treatment for anovulatory infertility in women with the polycystic ovary syndrome. Letrozole was also associated with higher live-birth and ovulation rates.
Ovulation induction with letrozole is associated with an ovulation rate of 70%-84% and a pregnancy rate of 20%-27% per cycle.
While in another study which Compare the Effect of Letrozole Alone with Letrozole Plus N-Acetylcystei...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Infertile women with PCOS
- • Normal hysterosalpingography
- • Normal semen analysis according to WHO parameters are major prerequisites
- Exclusion Criteria:
- • Infertile women with causes other than PCOS,
- • Ages \<18 or \>35 years
- • women taken confounding medications like other infertility drugs
- • Insulin sensitizers or hormones
- • Abnormal hysterosalpingography
- • Subnormal semen analysis
About Egymedicalpedia
eGymedicalpedia is a leading clinical trial sponsor dedicated to advancing medical research and innovation. With a focus on enhancing patient outcomes, eGymedicalpedia specializes in the design, implementation, and management of clinical trials across various therapeutic areas. The organization leverages cutting-edge technology and a robust network of healthcare professionals to ensure compliance with regulatory standards while prioritizing patient safety. Committed to transparency and collaboration, eGymedicalpedia aims to accelerate the development of groundbreaking treatments and therapies that address unmet medical needs.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported