Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF : Double Blinded, Randomized Control Trial

Launched by POTSAWAT SURABOTSOPON · Apr 15, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating whether giving a medication called Dexamethasone before a specific type of spine surgery, known as minimally invasive spine fusion surgery, can help reduce back pain after the operation. The goal is to see if this treatment can make the surgery more effective and improve recovery for patients with conditions like spinal stenosis and disc degeneration.

To participate in this trial, you need to be between 50 and 80 years old and scheduled for the surgery at one or two levels of your spine. However, if you’ve had previous spine surgery, have certain health conditions, or are allergic to similar medications, you may not be eligible. If you join the trial, you’ll receive either the Dexamethasone or a placebo (which looks like the medication but has no active ingredients) without knowing which one you’re getting, helping researchers understand the true effects of the treatment. This study is not yet recruiting participants, but it aims to provide valuable information on how to improve outcomes for patients undergoing spine surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age range: 50-80 years old.
• • Undergoing MIS TLIF surgery at 1-2 spinal levels.
• Exclusion Criteria:
• • Previously undergone spine surgery.
• • HbA1C greater than or equal to 7.5 mg%
• • Allergic to all types of experimental medication.
• • History of using systemic steroids.