Effect of Early Gait Training on Knee Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction

Launched by PEKING UNIVERSITY THIRD HOSPITAL · Apr 11, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how early gait training—essentially, the way people walk—can affect knee cartilage health after surgery to repair a torn anterior cruciate ligament (ACL). The goal is to understand if starting this training soon after surgery can help prevent deterioration of the cartilage in the knee, which is important for maintaining joint health. Researchers believe that by improving how people move, they can reduce the risk of long-term knee problems.

To participate in the study, patients need to meet specific criteria. They should be diagnosed with a first-time ACL tear confirmed by an MRI, be between 18.5 and 23.9 in body mass index (BMI), and have had their injury within the last six months. Participants should also be recovering well enough that their knee shows no major signs of inflammation or pain. This trial is currently looking for patients aged 65 to 74, and all genders are welcome. If someone joins the study, they can expect to receive guidance on early rehabilitation exercises aimed at improving their recovery and protecting their knee health in the long run.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with ACL rupture were diagnosed by MRI;
• • 2. Unilateral ACL rupture for the first time should be performed in our hospital (Department of Sports Medicine, Peking University Third Hospital)The art of reconstruction;
• • 3. Normal BMI range: 18.5-23.9 kg/m2;
• • 4. Within 6 months from the trauma;
• • 5. The affected knee joint has passed the acute stage, no obvious redness, pain,inflammation, and limited joint motion,basically restore joint motion.
• Exclusion Criteria:
• • 1. BMI\<18.5 kg/m2 or BMI≥24 kg/m2);
• • 2. There is a history of contralateral lower limb musculoskeletal system injury and surgery;
• • 3. ACL injury time \> 6 months;
• • 4. Outerbridge damage rating Ⅲ and Ⅳ;
• • 5. Patients with meniscal tears who are expected to undergo meniscal suture surgery at the time of ACLR surgery;
• • 6. Serious injury to the posterior cruciate ligament, medial collateral ligament, or lateral collateral ligament;
• • 7. There is metabolic syndrome (obesity, dyslipidemia, diabetes, etc.), which will involve articular cartilage Epidemic diseases, serious cardiovascular and cerebrovascular diseases, etc.;
• • 8. Those who do not want to accept this treatment