Result of tDCS in ASD Children With Comorbidities Like PANDAS, Rare Genetic Diseases or Autoimmune Disorders

Launched by SPANISH FOUNDATION FOR NEUROMETRICS DEVELOPMENT · Apr 11, 2024

Keywords

ClinConnect Summary

tDCS will be applied to 90 children diagnosed with ASD with Mu activity in one of their two temporal lobes and to another 90 children tDCS will not be applied but rather conventional treatments such as the Denver method, etc., in addition to collecting their electroencephalograms in eyes open condition, evoked potentials will be performed. with Mismatch Negativity paradigm to calculate the P300 wave every 25 sessions with a rest of 5-6 weeks between every 25 sessions and the changes in voltage and frequency of the EEG will be analysed using FFT \& PSD, as well as the latencies and amplitude...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 7 and 15 years old
• • Diagnosis: PDD, ASD or PANDAS
• • Have genetic alterations with geneticist reports like: mutation, random mating between organisms, random fertilization or crossing over (or recombination) between chromatids of homologous chromosomes during meiosis.
• • Natural birth without caesarean or complications
• • Normal Pregnancy
• Exclusion Criteria:
• • Head Trauma
• • Brain Injuries like meningitis or encephalitis, including SaRS, Herpes or MERS infections
• • Epilepsy
• • Rare Diseases with Auto-Immune Disease
• • Rare diseases with Endocrinology problems
• • Fever or Biochemical problems in the First Blood Test (First Visit)
• • Vaccines Reactions