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Search / Trial NCT06372249

A Clinical Trial of Soluble Fiber for Asthma

Launched by PHOENIX CHILDREN'S HOSPITAL · Apr 12, 2024

Trial Information

Current as of July 24, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial is studying whether adding a type of soluble fiber, called NOVELOSETM 3490, can help improve asthma symptoms in children aged 6 to 17. The researchers want to learn how diet, specifically fiber intake, might affect asthma by looking at samples from participants, such as blood, stool, and nasal wash. If your child is eligible for the study, they will be randomly assigned to receive either the soluble fiber or a placebo (a drink with no active ingredient) for several weeks. Participants will also fill out a dietary questionnaire to assess their fiber intake.

To be eligible, your child should have been diagnosed with asthma in the last two years and must meet certain health criteria, including having a specific level of a marker in their breath that indicates asthma severity. They should not have had any emergency visits for asthma in the past month and must be able to return for a follow-up visit after 4 to 6 weeks. This trial is still recruiting, so if you're interested, it's a good opportunity to learn more about how diet might play a role in managing asthma.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Between ages 6-17
  • Asthma diagnosis within the last 2 years
  • Fractional excretion of exhaled nitric oxide (FeNO) \> 50 ppb OR a clinical history of environmental allergies as defined by a positive skin prick or positive specific immunoglobulin E (IgE) tests to aeroallergens
  • No emergency department visits in the past 1 month
  • Ability to consume a liquid drink of fiber or placebo
  • Ability to return for a 4-6 week follow-up visit
  • No special or unique diet
  • Exclusion Criteria:
  • Cystic fibrosis
  • Bronchiectasis
  • Change in asthma medicines other than short acting bronchodilators planned over the next 4-6 weeks
  • Baseline estimated daily fiber intake less than or equal to 16 grams as determined by the ASA 24
  • Sibling of a participant already enrolled in the study

About Phoenix Children's Hospital

Phoenix Children's Hospital is a leading pediatric healthcare institution dedicated to advancing child health through innovative research and clinical trials. With a commitment to providing exceptional care, the hospital leverages its extensive expertise in pediatric medicine to conduct rigorous clinical studies that aim to improve treatment outcomes and enhance the quality of life for children facing various health challenges. As a recognized center of excellence, Phoenix Children's Hospital collaborates with a network of healthcare professionals, researchers, and academic institutions to foster groundbreaking discoveries and ensure access to cutting-edge therapies for young patients.

Locations

Phoenix, Arizona, United States

Patients applied

0 patients applied

Trial Officials

Matthew Rank

Principal Investigator

Phoenix Children's

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported