Improving Quality of Life in Older Patients With Frailty and Hematological Cancer Through Geriatric Assessment
Launched by ODENSE UNIVERSITY HOSPITAL · Apr 17, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
The Improve study is looking at how to help older patients with blood cancers, like leukemia or lymphoma, improve their quality of life. Specifically, it is comparing two groups: one group will receive standard cancer treatment along with a thorough evaluation and special care tailored for older adults, while the other group will only receive the usual cancer treatment. The goal is to see if adding this extra support helps these patients function better after 12 weeks.
To participate in the study, you must be at least 70 years old and have been recently diagnosed with certain types of blood cancer. You should also be starting cancer treatment soon and have a specific score that shows you are frail but still able to live for at least six more months. If you join the study, you will be randomly assigned to one of the two groups and will receive care as part of the research. This trial is currently recruiting participants, and it aims to find better ways to care for older patients facing these serious health challenges.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age ≥70 years
- • New diagnosis or progression/relapse of acute leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, myelodysplastic syndrome, lymphoma, multiple myeloma, chronic myelomonocytic leukemia or myelofibrosis
- • Scheduled systemic cancer treatment or initiated systemic cancer treatment within 6 weeks
- • Geriatric 8 frailty score of ≤14 at screening
- • Life expectancy \> 6 months
- • Not hospitalized at the time of inclusion
- Exclusion Criteria:
- • Current systemic treatment for other coexisting cancer. Patients receiving anti-hormone treatment for breast cancer or prostate cancer are not excluded, if no evidence of disease progression (radiological/biochemical) in past 3 months or if treatment is adjuvant.
- • Having consulted a geriatric outpatient clinic past 6 months
- • Patients in need of specialized neuro-rehabilitation
- • Unable to understand Danish
- • Unable to give written informed consent
About Odense University Hospital
Odense University Hospital is a leading academic medical center located in Denmark, dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital is committed to enhancing patient outcomes and fostering collaboration among multidisciplinary teams. With a focus on translating scientific discoveries into practical applications, Odense University Hospital leverages its state-of-the-art facilities and expertise to conduct rigorous trials across various medical fields, ensuring adherence to the highest ethical and regulatory standards. Through these efforts, the hospital aims to contribute significantly to the global body of medical knowledge and improve the quality of care for patients both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Odense C, , Denmark
Patients applied
Trial Officials
Henrik Frederiksen
Principal Investigator
Odense University Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported