Prospective Cohort Study of Complications and Outcomes in Cirrhosis

Launched by NANFANG HOSPITAL, SOUTHERN MEDICAL UNIVERSITY · Apr 16, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the complications and outcomes in patients with a severe liver condition called decompensated cirrhosis. The researchers want to understand how common certain complications are, such as infections and issues with brain function, and what factors might increase the risk of these complications. Patients who participate will be closely monitored during their hospital stay and will receive follow-up phone calls 30 and 90 days after they leave the hospital to check on their health.

To be eligible for this study, participants must be between 18 and 80 years old and have a diagnosis of cirrhosis along with complications like fluid buildup or bleeding. However, individuals with certain conditions, such as cancer or those who have received organ transplants, cannot take part in this trial. Overall, this research aims to improve understanding and treatment for patients facing serious complications from cirrhosis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Informed written consent
• • Age between 18 years and 80 years
• • Cirrhosis based on liver histology or a combination of characteristic clinical, biochemical, and imaging features
• • Complications of decompensated cirrhosis (ascites, gastrointestinal bleeding and hepatic encephalopathy)
• Exclusion Criteria:
• • Malignancy
• • Acquired immune deficiency syndrome
• • Received immunosuppressive drugs for non-hepatic reasons
• • Received organ transplantations