An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough

Launched by HULL UNIVERSITY TEACHING HOSPITALS NHS TRUST · Apr 16, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different types of cough can affect patients with chronic cough, which is a cough lasting more than eight weeks. Researchers have created a new questionnaire that helps identify four distinct cough patterns and allows patients to describe their own cough experiences. The goal is to see if patients can easily understand and complete the questionnaire on their own. This information will help doctors understand how severe and disruptive the cough is for each patient.

To participate in this study, individuals must be over 18 years old and have had a cough for at least eight weeks. They should have a clear chest X-ray from the last two years and must not be current or recent smokers. Participants will fill out the questionnaire initially and again six weeks later to see if their responses are consistent. This study is important because it aims to better understand chronic cough and how it affects daily life, ultimately leading to improved care for patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Male and female patients \> 18yrs of age
• • 2. Patients with a current cough of at least 8 weeks duration
• • 3. Patients with a clear chest X-Ray within previous 2 yrs
• • 4. Non- smoker
• • 5. Able to understand and comply with the requirements of the study and sign Informed Consent forms.
• • 6. Good understanding of written and spoken English -
• Exclusion Criteria:
• • 1. Recent respiratory tract infection (\<4 weeks prior).
• • 2. Current smokers or ex-smokers with \<6 months' abstinence prior to Study.
• • 3. Any clinically significant or unstable medical or psychiatric condition that would, in the opinion of the investigator, interfere with the subject's ability to participate in the study safely.
• • 4. Participation in any clinical research study evaluating an investigational drug or therapy within 30 days or within 5 half-lives (whichever is longer) of the investigational drug prior to Study visit. If the subject was in an observational clinical study no washout is required.
• • 5. Subjects who, in the opinion of the Investigator, should not participate in the study for any other reason.