Effect of Oral Lactate Ingestion on Appetite Regulation

Launched by WILFRID LAURIER UNIVERSITY · Apr 17, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how drinking a solution containing lactate, a substance found in some foods, affects feelings of hunger and appetite. Researchers want to see if lactate can change the way our bodies regulate appetite compared to a placebo, which is a harmless salt solution. Participants will drink either the lactate solution or the placebo, and then their blood will be tested and their appetite assessed over 90 minutes. Additionally, researchers will track how much food participants eat over three days surrounding each session to get a complete picture of their eating habits.

To be eligible for this study, participants should be healthy adults aged 18 to 65, as determined by a simple activity questionnaire. For women, it's important that they have regular menstrual cycles. People who take certain supplements or medications that affect metabolism, are pregnant, or have had a pregnancy in the last three years won't be able to participate. The study is not yet recruiting participants, but it aims to provide insights into appetite control, which could help in understanding eating behaviors in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Deemed healthy using Canadian Society for Exercise Physiology Get Active Questionnaire
• • Female participants must be eumenorrheic (menstrual cycle length between 21-35 days)
• Exclusion Criteria:
• • Failure to meet inclusion criteria
• • Taking supplements or medications known to affect metabolism (e.g., creatine, beta-blockers)
• • Currently pregnant or a pregnancy of \>3 months within the last 3 years,