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Search / Trial NCT06380075

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

Launched by UNIVERSITY OF WISCONSIN, MADISON · Apr 18, 2024

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying two different ultrawide field cameras that take pictures of the back of the eye to see how well they work for checking and monitoring inherited retinal diseases (IRDs). The main goal is to find out if these cameras can give the same useful information as the standard imaging system that doctors typically use. Participants in the study will have their pupils dilated (which means their eyes will be widened to see better inside) and then have photographs taken of their eyes using three different cameras.

To be eligible for the trial, participants need to be at least 18 years old and have a clinical or genetic diagnosis of an inherited retinal disease. They also need to be willing to sign a consent form to participate. However, people with certain other eye conditions, those who can’t fixate for imaging, or those who do not wish to participate will not be included. This study is currently looking for participants, and it offers a chance to contribute to important research that could improve how we monitor eye health in individuals with inherited retinal diseases.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Participants 18 years and older with a clinical and/ or genetic diagnosis of IRD recruited either from the clinic and/or the Inherited Ocular Disease Registry to participate in this trial
  • Participants that are willing to participate as evidenced by signing the written informed consent
  • Exclusion Criteria:
  • Presence of ocular conditions other than an IRD which may affect the quality of ocular imaging including but not limited to advanced cataracts, corneal disorders, nystagmus, vitreous hemorrhage, or poor dilation
  • Presence of ocular conditions other than an IRD which may affect interpretation of retinal imagining including but not limited to epiretinal membrane, choroidal neovascular membrane, or macular scarring
  • Patients with advanced IRDs who are unable to fixate for imaging
  • Patients unable to tolerate ocular imaging
  • Patients who do not wish to participate

About University Of Wisconsin, Madison

The University of Wisconsin-Madison is a leading research institution renowned for its commitment to advancing healthcare through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university leverages its extensive resources, including cutting-edge facilities and a diverse pool of expert researchers, to conduct rigorous studies that address critical health challenges. The institution's focus on translating research findings into practical applications fosters the development of new treatments and interventions, ultimately contributing to improved patient outcomes and public health initiatives. As a sponsor of clinical trials, the University of Wisconsin-Madison is dedicated to upholding the highest ethical standards and ensuring participant safety throughout the research process.

Locations

Madison, Wisconsin, United States

Patients applied

0 patients applied

Trial Officials

Kimberly Stepien, MD

Principal Investigator

University of Wisconsin, Madison

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported