The Role of the Human Microbiome in Patients After Pancreatic Resection.

Launched by ST. ANTONIUS HOSPITAL · Apr 19, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how the bacteria and other microorganisms found in our bodies, known as the microbiome, can affect patients after they have surgery for pancreatic cancer. The researchers want to see if the different types of microorganisms present in a patient's saliva, stool, blood, and bile can help predict whether they are at high or low risk for complications after surgery. By analyzing samples taken at various times, the team hopes to understand how the microbiome changes and how those changes may relate to recovery and complications.

To participate in this study, you need to be an adult (ages 65-74) who has a type of pancreatic cancer that can be treated with surgery. You should be willing to follow the study guidelines and allow the researchers to access your medical information. It's important to note that if someone cannot give informed consent—meaning they understand and agree to participate, perhaps due to language barriers or literacy issues—they will not be able to join the study. If you decide to participate, you can expect to provide samples at different times and help researchers learn more about the role of the microbiome in recovery after pancreatic surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patient with a resectable, borderline resectable or locally advanced pancreatic and periampullary presumed (pre)malignancy.
• • The intention of the treatment must be curative including surgery and (neo-)adjuvant chemotherapy.
• • Willing and able to adhere to the study procedures described in this protocol and to grant the study team access to the electronic patient file and other data that are required to answer the research questions described in this protocol.
• Exclusion Criteria:
• • Inability to provide adequate informed consent (e.g. language barrier, illiteracy)