Selection Protocol for Liver Transplantation in Patients Aged Over 70 Years

Launched by AZIENDA OSPEDALIERA DI PADOVA · Apr 22, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new way to select patients over 70 years old who need a liver transplant. As more older adults are living longer, the number of liver transplants in this age group is increasing. However, older patients often have other health issues that can make it more complicated to choose who is suitable for a transplant. The trial aims to create a step-by-step process to help doctors decide which elderly patients would benefit most from a liver transplant.

To be eligible for this trial, participants must be between 70 and 75 years old and need a liver transplant from a deceased donor due to severe liver disease or a liver tumor. This will be their first liver transplant. Unfortunately, those who are under 70, have previously received a liver transplant, or are getting a transplant from a living donor cannot participate. If someone joins the study, they will go through a thorough evaluation to see if they meet the criteria for the transplant. This trial could help improve the process of selecting liver transplant candidates in the future, making it safer and more effective for older patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age \>70 years and ≤ 75 years
• • Liver transplant from cadaveric donor
• • First liver transplant
• • End stage liver disease or liver tumor
• Exclusion Criteria:
• • Age ≤ 70 years
• • Living donor liver transplant
• • Previous liver transplant
• • Liver transplant for acute liver failure