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Search / Trial NCT06385275

The Role of Vitamin K on Knee Osteoarthritis Outcomes

Launched by BOSTON UNIVERSITY · Apr 24, 2024

Trial Information

Current as of July 24, 2025

Recruiting

Keywords

Vitamin K 1 Vitamin K 2 Menaquinone 7 (Mk 7) Uncarboxylated Matrix Gla Protein (Uc Mgp) Phylloquinone

ClinConnect Summary

This clinical trial is studying the effects of different types and amounts of vitamin K on knee osteoarthritis (OA) in older adults. Osteoarthritis is a common condition that causes pain and stiffness in the knees, and researchers want to find out if vitamin K can help improve outcomes for people with this condition. They will test two types of vitamin K—K1 and K2—at different doses to see if they can make a difference in knee health.

To be eligible for this trial, participants must be at least 60 years old and have a clinical diagnosis of knee osteoarthritis. They also need to be able to speak English. Unfortunately, those who are taking blood-thinning medications like warfarin or other similar drugs cannot participate. If you join the study, you can expect to receive vitamin K supplements and have your health monitored over time to see how it affects your knee OA. This trial is currently recruiting participants, and it aims to gather important information that could help improve treatment options for older adults with knee osteoarthritis.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • ≥60 years old
  • Clinical diagnosis of knee OA by the treating rheumatologist
  • English fluency
  • Exclusion Criteria:
  • Anticoagulation use (including warfarin, dabigatran, rivaroxaban, apixaban)

About Boston University

Boston University, a leading research institution located in Boston, Massachusetts, is dedicated to advancing health sciences through innovative clinical trials and research initiatives. With a strong emphasis on interdisciplinary collaboration, the university leverages its extensive network of experts and state-of-the-art facilities to conduct rigorous clinical studies aimed at improving patient outcomes and addressing pressing health challenges. Boston University is committed to ethical research practices, patient safety, and the dissemination of findings to foster greater understanding and advancements in medical care.

Locations

Boston, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

Jean Liew, MD MS

Principal Investigator

Boston University Chobanian & Avedisian School of Medicine, Department of Rheumatology

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported