Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy With Chronic Lung Diseases

Launched by UNIVERSITY OF ZURICH · Apr 22, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how exercise performance is affected when patients with chronic lung diseases breathe regular air compared to using low-flow oxygen therapy during submaximal exercise. Essentially, the researchers want to understand if patients can exercise better or feel more comfortable when they use supplemental oxygen while being active.

To join the study, participants must be at least 18 years old and have a diagnosed chronic lung disease. They should have experienced a drop in oxygen levels during exercise but are currently stable on their medications. However, people who need extra oxygen all the time, are pregnant, or have certain health issues that would prevent them from following the study procedures can't participate. If eligible, participants will be asked to take part in exercises while their oxygen levels and overall performance are monitored. This research could help improve how exercise is managed for people with lung diseases in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Minimum 18 years of age
• • Written informed consent
• • Patients with diagnosed chronic lung disease
• • Former desaturation under exercise defined as Spo2-decrease \>3%- Page 3 of 4
• • Treated with a stable drug therapy (with no changes for at least 14 days prior to screening)
• Exclusion Criteria:
• • Severe hypoxemia needing supplemental oxygen therapy defined as (partial pressure of Oxygen (PaO2) \< 6.9 KiloPascal (kPa)
• • Pregnancy
• • Unability or contraindications to undergo the investigated intervention
• • Unability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc.