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Search / Trial NCT06385834

The Effect of Morning vs Evening Aerobic Exercise Training on Cardiac Remodeling and Function Improvement in Patients After ST Elevation Myocardial Infarction

Launched by RENJI HOSPITAL · Apr 22, 2024

Trial Information

Current as of July 26, 2025

Recruiting

Keywords

Circadian Rhythm St Segment Elevation Myocardial Infarction Aerobic Exercise

ClinConnect Summary

This clinical trial is studying how the timing of aerobic exercise—whether in the morning or evening—affects heart recovery in patients who have recently had a heart attack known as ST-segment Elevation Myocardial Infarction (STEMI). The goal is to find out which time of day is better for patients to exercise for improving their heart function and overall health after they have undergone treatment to restore blood flow to the heart.

To participate in this study, individuals need to be between 18 and 75 years old and have experienced typical symptoms of a heart attack within the last 24 hours. They should have had successful treatment to reopen blocked arteries and must be in relatively stable health with certain heart function measures. Participants will be asked to follow specific exercise routines based on the time of day they are assigned. This trial is currently looking for volunteers, so if you or a loved one fits the criteria and are interested in helping improve heart recovery knowledge, this could be a valuable opportunity.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Between 18 and 75-years-old;
  • Typical symptoms of acute myocardial infarction within 24 hours, with ST segment elevation of ≥1mm in two consecutive leads on electrocardiogram
  • After receiving complete revascularization treatment
  • Cardiac function grading I to II without any other serious complications
  • Left ventricular ejection fraction \>30%
  • Compliant with the guidelines of the American College of Cardiology/American Heart Association for participating in cardiac rehabilitation standards
  • Signed written informed consent.
  • Exclusion Criteria:
  • Patients with unstable angina
  • severe symptomatic congestive heart failure detectable myocardial ischemia
  • valvular disease requiring surgery
  • severe ventricular arrhythmias
  • severe concomitant life-threatening diseases such as cancer, and rheumatoid disease
  • osteoarticular diseases that may affect the exercise process

About Renji Hospital

Renji Hospital, a prestigious medical institution affiliated with Shanghai Jiao Tong University School of Medicine, is dedicated to advancing healthcare through innovative clinical research. With a strong emphasis on patient-centered care, Renji Hospital conducts a wide range of clinical trials across various therapeutic areas, harnessing cutting-edge technology and evidence-based practices. The hospital's multidisciplinary team of experienced researchers and medical professionals collaborates closely to ensure rigorous study design and execution, aiming to contribute significantly to medical knowledge and improve treatment outcomes for patients worldwide.

Locations

Shanghai, , China

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported