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Search / Trial NCT06386991

Effect of Different Irrigation Solutions on Postoperative Pain and Lesion Healing

Launched by TC ERCIYES UNIVERSITY · Apr 24, 2024

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how different cleaning solutions used during dental treatment can affect pain and healing in molar teeth that have a specific type of damage called necrotic open apex. The researchers will use three types of solutions—EDTA, Etidronic Acid, and Citric Acid—to see which one helps patients feel better after treatment and promotes healing over a year.

To participate, candidates should be between 8 and 15 years old, have molar teeth with open tips that need treatment, and should not have any major health issues or gum disease. It’s important that these teeth have not been treated before and that participants haven’t taken certain medications recently. If you join the study, you can expect to receive one of the irrigation solutions during your treatment and to be monitored for a year to track your pain levels and how well your teeth heal. This trial is currently recruiting participants, and both boys and girls can take part.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:• Molars with open apex
  • Teeth with apical periodontitis
  • Teeth for which prosthetic restoration is not planned
  • Patients between the ages of 8-15 who do not have any significant health problems
  • Patients who are not accompanied by periodontal problems and have good oral hygiene
  • Exclusion Criteria:• People with systemic disease and allergic reactions
  • Severely damaged teeth
  • If the tooth has previously undergone root canal treatment.
  • Use of antibiotics, anti-inflammatory and painkillers in the last two weeks

About Tc Erciyes University

TC Erciyes University is a leading academic institution in Turkey, dedicated to advancing medical research and healthcare through innovative clinical trials. With a strong emphasis on scientific excellence and collaboration, the university leverages its state-of-the-art facilities and multidisciplinary expertise to conduct rigorous studies aimed at improving patient outcomes. Committed to ethical standards and regulatory compliance, TC Erciyes University fosters a research environment that promotes the development of new therapies and interventions, contributing significantly to the global medical community.

Locations

Kayseri, , Turkey

Patients applied

0 patients applied

Trial Officials

ERASLAN AKYÜZ

Principal Investigator

BAŞ ARAŞTIRMACI

ÜSTÜN

Study Director

YÜRÜTÜCÜ

EMİNSOY AVCI

Study Chair

YARDIMCI ARAŞTIRMACI

SOLAK KOLÇAKOĞLU

Study Chair

YARDIMCI ARAŞTIRMACI

KIZILCI

Study Chair

YARDIMCI ARAŞTIRMACI

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported