68Ga-PSFA PET Imaging in Patients With PSMA/FAP Positive Disease

Launched by FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY · Apr 24, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging tool called 68Ga-PSFA, which is designed to help doctors see and diagnose certain types of cancer that express specific markers known as PSMA and FAP. The trial aims to evaluate how safe this imaging method is, how well it spreads throughout the body, and how useful it is in identifying cancerous lesions. By using this advanced imaging technique, researchers hope to improve the diagnosis and understanding of diseases that show these markers.

To participate in this study, individuals need to be at least 18 years old and provide their written consent to join. Eligible participants should have a suspected or newly diagnosed cancer that shows either PSMA or FAP positivity, which can be confirmed with tests like MRI, CT scans, or pathology reports. However, people with non-cancerous conditions, those who are pregnant, or anyone who cannot give consent will not be able to take part. Participants can expect to undergo imaging tests and be closely monitored throughout the trial to ensure their safety and gather important information about the effectiveness of this new imaging method.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. At least 18 years of age.
• • 2. Signed informed consent.
• • 3. Patients with suspected or newly diagnosed or previously malignant disease, with either PSMA or FAP positive expression (supporting evidence may include MRI, CT, and pathology report, etc).
• Exclusion Criteria:
• • 1. Patients with non-malignant disease.
• • 2. Patients with pregnancy.
• • 3. The inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.
• • 4. Known or expected hypersensitivity to 68Ga-PSFA or any of its components.
• • 5. Any serious medical condition or extenuating circumstance which the investigator feels may interfere with the procedures or evaluations of the study.