Arresting Carious Lesions With Minimal Intervention Techniques
Launched by NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS · Apr 24, 2024
Trial Information
Current as of July 22, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial, titled "Arresting Carious Lesions With Minimal Intervention Techniques," is looking into two gentle treatment methods for young children with tooth decay, specifically in their back teeth (molars). The goal is to see how well these methods work over a year in stopping the decay. One method uses a special solution to help remove the decay, while the other uses a different solution to halt its progress. This study will involve children aged 4 to 8 years who have at least two decayed back teeth that are not too severely damaged.
If your child qualifies, they will participate in a friendly study where they will receive one of the two treatments. The researchers will monitor their progress through check-ups and X-rays over the next year to see how effective each treatment is. It's important to note that children with certain medical conditions or allergies, as well as those younger than 4 or older than 8, won't be included in the study. This trial is not yet recruiting participants, but it represents an important step toward finding safer, less invasive ways to treat tooth decay in children.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Children aged 4 to 8 years with a non-contributary medical history and sufficient compliance for the caries treatment will be included. The eligible children should have at least two carious primary molars (cavitated lesions up to 2/3 of dentin, corresponding to ICDAS 5 and 6) on different quadrants without any periapical pathology detected radiographically.
- Exclusion Criteria:
- • Children aged below 4 years and above 8 years, with compromised medical history and/or allergies, with clinical or radiographic signs or symptoms of pulp pathology and with developmental dental defects will be excluded.
About National And Kapodistrian University Of Athens
The National and Kapodistrian University of Athens is a prestigious academic institution in Greece, renowned for its commitment to advancing medical research and education. With a strong emphasis on interdisciplinary collaboration, the university fosters innovative clinical trials aimed at improving healthcare outcomes. Its dedicated research teams leverage cutting-edge methodologies and a diverse range of expertise to address critical health challenges. As a clinical trial sponsor, the university prioritizes ethical standards and the welfare of participants, contributing significantly to the global body of medical knowledge and the development of new therapeutic interventions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Sotiria Gizani, Assoc Prof
Principal Investigator
Department Of Paediatric Dentistry, National And Kapodistrian University Of Athens
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported