Light Stimulation to Improve Visual Function After Optic Neuritis in Persons with Multiple Sclerosis

Launched by TECHNICAL UNIVERSITY OF MUNICH · Apr 25, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to help people with multiple sclerosis (MS) improve their vision after experiencing optic neuritis, which is inflammation of the optic nerve that can cause vision problems. The study involves using light stimulation to see if it can help restore visual function in patients who have had optic neuritis within the last 1 to 3 months. Participants will be randomly assigned to either receive light stimulation daily for 12 days or to a control group that does not receive the light treatment.

To be eligible for this study, participants must be between 18 and 60 years old, have a diagnosis of relapsing-remitting multiple sclerosis or related conditions, and have experienced optic neuritis recently. Those with certain conditions, like epilepsy or specific eye diseases, will not be able to participate. If you join the trial, you will be asked to watch a flickering light video on your mobile phone as part of the treatment, and the researchers will monitor changes in your vision to understand how effective the light stimulation is. This study is currently recruiting participants, and it aims to gather important information on how light can potentially aid recovery of vision after optic neuritis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Relapsing remitting multiple sclerosis or clinically isolated syndrome or no indication of chronic inflammatory central nervous system disease
• • Age 18-60 years
• • Optic neuritis within 1-3 months
• Exclusion Criteria:
• • Epilepsy
• • Light-triggered migraine
• • Insufficient vision correction
• • Retinal disease (glaucoma, macular edema, macula degeneration, ...)