Evaluation of Accelerated Sampling Techniques for Vessel Wall Imaging

Launched by UNIVERSITY OF PENNSYLVANIA · Apr 25, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new, faster way to take pictures of blood vessel walls using MRI (Magnetic Resonance Imaging). The goal is to see if this quicker method can give us better images to help diagnose conditions related to blood vessels, especially in patients with vasculopathy, which is a disease that affects blood vessels.

To participate in this study, you need to be at least 18 years old and already scheduled for an MRI of your blood vessels as part of your regular medical care. However, if you have certain medical devices in your body, have serious health issues, or are pregnant or breastfeeding, you won't be eligible to join. If you decide to participate, you can expect to undergo a standard MRI scan, but with a new technique that aims to improve the quality of the images taken. This study is currently recruiting participants, and everyone is welcome regardless of gender.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients 18 years of age and scheduled to undergo clinical vessel wall MR imaging exams as part of their standard of care.
• Exclusion Criteria:
• • 1. Any person under the age of 18
• • 2. Presence of artifact-producing intracranial devices (aneurysm clips/coils, ventricular drains, craniectomy mesh, etc.)
• • 3. Any person with contraindications to MRI (medical instability, non-MRI compatible implanted devices, retained metallic foreign bodies, claustrophobia)
• • 4. Large space-occupying lesions (50 mL) or substantial mass effect (herniation, 5mm midline shift) on preceding brain imaging,
• • 5. Imminently life-threatening co-morbid conditions
• • 6. A history of premorbid disabling neurological or psychiatric disease, current substance abuse or remote substance abuse with permanent organic sequelae
• • 7. Pregnancy or lactation