Effects of Brazil Nut Supplementation in Patients With Chronic Kidney Disease Undergoing Conservative Treatment

Launched by UNIVERSIDADE FEDERAL FLUMINENSE · Apr 27, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how Brazil nut supplementation may help patients with chronic kidney disease (CKD) who are receiving conservative treatment. The focus is to see if taking Brazil nuts can reduce inflammation, lower oxidative stress (which is related to cell damage), and improve gut health by looking at the intestinal microbiota, which is the community of bacteria living in our intestines.

To participate in this study, you must be a patient who has been monitored for nutrition for more than three months at a specific clinic and be in stages G3a to G4 of chronic kidney disease. However, if you have taken antibiotics, anti-inflammatory drugs, or antioxidant supplements in the last three months, or have certain allergies or health conditions, you may not be eligible. If you join the trial, you will likely be asked to take Brazil nuts and may be monitored for any changes in your health related to inflammation and gut health. This study is in the planning stage, so they are not recruiting participants yet, but it aims to provide valuable insights into managing kidney disease.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with more than three months of nutritional monitoring at the Renal Nutrition Outpatient Clinic of the Universidade Federal Fluminense (UFF), between stages G3a and G4, will be included, according to KDOQI 2020 guidelines, and authorized by the medical and nutritionist team.
• Exclusion Criteria:
• • Current use or in the last three months of antibiotics, anti-inflammatories and/or antioxidant supplements. Patients who are allergic, intolerant, or regularly ingest Brazil nuts; pregnant/lactating women, smokers; undergoing cancer treatment, HIV-positive, or with any clinical condition that compromises the accuracy of the intervention.