Effect of New High Ankle Block on Wound Healing After the Operation of Debridement of Diabetes Foot

Launched by XUZHOU CENTRAL HOSPITAL · May 1, 2024

Keywords

ClinConnect Summary

This study is testing whether using a high ankle nerve block (a numbing shot near the ankle) during foot debridement surgery for diabetic foot ulcers helps wounds heal faster and improves blood flow in the leg, compared with the usual general anesthesia. It’s a randomized, single-blind trial, meaning participants are randomly assigned to either the nerve block or the standard anesthesia and the people measuring the outcomes don’t know which group you’re in. The main thing they’re looking at is the change in foot ulcer size, measured before surgery and then on postoperative days 1 and 14. They’ll also check blood flow in the leg, skin temperature, and pain at several time points after surgery.

Who can join: adults with diabetes and a diabetic foot ulcer (Wagner grade 2–4) who can communicate well and follow the study procedures. Exclusions include a skin infection at the planned nerve block site, serious heart or brain blood vessel disease, bleeding or clotting problems, or mental impairment. If enrolled, you’ll be randomly assigned to the high ankle block or to general anesthesia. The high ankle block involves ultrasound-guided nerve blocks to numb the leg before surgery; the other group receives standard general anesthesia. After surgery, researchers will photograph the ulcer, measure blood flow with ultrasound, and check skin temperature and pain on days 1, 7, and 14. The study is at Xuzhou Central Hospital in China, expects about 70 participants, and results are not yet available.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • refer to the 2019 World Guide for the Prevention and Treatment of diabetes Feet (DF), DF patients who meet the diagnostic criteria were Wagner's grade 2-4, good communication skills and ability to co-operate in completing various monitoring operations.
• Exclusion Criteria:
• • Skin infection at the puncture site; Concomitant severe cardiovascular and cerebrovascular diseases; Significant abnormalities in coagulation function; Mental abnormalities; Dementia and cognitive impairment.