Comparison of Progestin Primed Ovarian Stimulation (PPOS) vs.GnRH Antagonist Methods on IVF Outcomes

Launched by NESTA CLINIC · Apr 29, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at two different methods for preparing women for in vitro fertilization (IVF) to see which one helps achieve better outcomes. The two methods being compared are Progestin Primed Ovarian Stimulation (PPOS) and GnRH Antagonist. The goal is to find out which method leads to more successful embryo development for women facing fertility issues.

To participate in the trial, women should be between the ages of 18 and 39, have a body mass index (BMI) between 18 and 35, and be willing to use thawed embryos for their treatment. However, if a woman has certain health conditions, such as a significant weight issue (BMI over 30) or specific reproductive tract problems, she may not be eligible. Participants will receive either of the two stimulation methods and will be monitored throughout the process to see how well the embryos develop. This trial is not yet recruiting, but it aims to help improve IVF treatments for women trying to conceive.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • BMI \> 18 kg/m2 ve \<35 kg/m2
• • Couples that accept being included in the study
• • Couple accepting thawed embryo transfer
• Exclusion Criteria:
• • Known chromosomal abnormality in either member of the couple
• • Couples with unexplained infertility
• • BMI \> 30 kg/m2
• • Mullerian malformations
• • Undergoing oocyte cryopreservation for medical reasons (such as malignancies)
• • Couple insists on fresh embryo transfer