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Search / Trial NCT06396767

Diaphragmatic Inspiratory Amplitude as a Prognosticator for Postoperative Pulmonary Complications After Cardiac Surgery

Launched by LONDON HEALTH SCIENCES CENTRE RESEARCH INSTITUTE OR LAWSON RESEARCH INSTITUTE OF ST. JOSEPH'S · Apr 30, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how the movement of the diaphragm, the main muscle used for breathing, can help predict complications after heart surgery. After cardiac surgery, some patients can develop problems with their lungs, known as Postoperative Pulmonary Complications (POPCs). Researchers want to see if measuring how well the diaphragm expands when breathing can help identify patients at risk for these complications. They will use a special ultrasound technique to monitor diaphragm movement in real-time, which could lead to quicker interventions if needed.

To participate in this study, you must be over 18 years old and scheduled for elective heart surgery. Certain patients, such as those with specific pre-existing conditions, those undergoing emergency surgeries, or those needing heart transplants, are not eligible. If you join the trial, you can expect to have your diaphragm's movement monitored before and after your surgery, which may help improve care for future patients. Your participation could contribute to better understanding and management of lung issues following heart surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All patients aged\>18 years and undergoing elective cardiac surgery.
  • Exclusion Criteria:
  • 1. . Redo Cardiac surgery.
  • 2. . Pre-existing CNS disease (like Parkinson's disease) or Brain injury or Psychiatric disorder
  • 3. . Emergency cardiac surgery
  • 4. . Surgeries done via Thoracotomy approach.
  • 5. . Pre-surgery ICU stay/ on NIV/ on mechanical ventilation.
  • 6. . Pre-surgery Hemodynamic instability requiring vasopressors/IABP institution.
  • 7. . Age\<18
  • 8. . Elevated hemidiaphragm before surgery on chest x ray
  • 9. . Pre-existing neuromuscular disorders (like myasthenia gravis etc.)
  • 10. . Patients planned for heart transplantation.
  • 11. . Patients on mechanical circulatory support preoperatively (intra-aortic balloon pump, extracorporeal membrane oxygenation, or ventricular assist device).
  • 12. . Inability to give consent.

About London Health Sciences Centre Research Institute Or Lawson Research Institute Of St. Joseph's

The London Health Sciences Centre Research Institute, affiliated with Lawson Health Research Institute at St. Joseph's Health Care, is dedicated to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into practical applications, the institute fosters collaboration among leading researchers, clinicians, and healthcare professionals. It aims to improve patient outcomes and enhance the quality of care through rigorous investigation in areas such as cancer, cardiovascular health, and neuroscience. By integrating cutting-edge research with clinical practice, the institute plays a pivotal role in shaping the future of healthcare delivery in the community and beyond.

Locations

London, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Raffael Zamper, MD

Principal Investigator

Western University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported