Effect of Combining Peri-hamstring Injection or Anterior Obturator Nerve Block on the Analgesic Efficacy of Adductor Canal Block for Arthroscopic Anterior Cruciate Ligament Reconstruction Under General Anesthesia
Launched by AIN SHAMS UNIVERSITY · May 1, 2024
Trial Information
Current as of August 22, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at different ways to manage pain after a specific knee surgery called anterior cruciate ligament (ACL) reconstruction. The researchers want to see if combining two different pain relief methods—an injection around the hamstring area and a block of a nerve in the front of the thigh—can help reduce pain better than just one method alone. This is important because patients often experience pain not only from the surgery itself but also from where the graft is taken from their hamstring.
To participate in this trial, you need to be between 21 and 70 years old and scheduled for this knee surgery. You should be generally healthy, without any severe medical conditions or allergies to the medications used in the study. If you choose to join, you will receive one of the pain relief methods during your surgery and then be monitored for pain levels afterward. This trial aims to find the best way to keep patients comfortable after surgery, which can help improve recovery and overall experience.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Age 21-70 years
- • 2. Both sex
- • 3. Patients scheduled for elective arthroscopic anterior cruciate ligament reconstruction under general anesthesia.
- • 4. American Society of Anesthesiologists Physical Status Class I, II Patients.
- • 5. Body Mass Index \<30 kg/m2.
- Exclusion Criteria:
- • 1. History of allergy to the study medications.
- • 2. American Society of Anesthesiologists class ≥III.
- • 3. Patients refusal to participate in the study.
- • 4. The inability to comprehend or participate in the pain scoring system.
- • 5. Contraindications to regional anesthesia (including coagulopathy and local infection).
- • 6. Psychiatric disorder and patient with any neurological disorder.
- • 7. Opioid tolerance or dependence.
- • 8. Distorted anatomy.
- • 9. Peripheral neuropathy.
- • 10. Renal or hepatic impairment.
- • 11. Morbid obesity (Body Mass Index: \>30kg/m2).
- • -
About Ain Shams University
Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported