Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

Launched by DUKE UNIVERSITY · May 1, 2024

Keywords

ClinConnect Summary

This clinical trial is focused on improving outcomes for lung transplant patients by studying the experiences of both donors and recipients. Researchers want to gather detailed information, including clinical data, blood samples, and feedback from patients, from around 2,600 people involved in lung transplants across various centers. The main goal is to understand how differences in donor practices and medical care can affect the success of lung transplants and to identify specific blood markers that may predict complications after the surgery.

To participate in this study, you need to be at least 18 years old and either a candidate for a lung transplant, currently on the waiting list, or have received a lung transplant within the past 30 days. It's also important that you can give informed consent, meaning you understand the study and agree to participate. Participants can expect to contribute valuable information that might help future lung transplant patients and improve overall care. If you're interested or think you may qualify, please talk to your healthcare provider for more details.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Able to understand and provide informed consent
• • 2. ≥ 18 years of age at the time of written informed consent
• • 3. Anticipated listing or listed for a single or bilateral cadaveric donor lung transplant or having received a lung transplant within 30 days
• • Participants undergoing repeat lung transplantation or multi-organ transplantation are eligible if they meet the inclusion/exclusion criteria.
• Exclusion Criteria:
• • 1. Unwillingness of a participant or legally authorized representative (LAR) to give written informed consent or comply with study protocol
• • 2. Pregnancy or plans to become pregnant
• • 3. Past or current medical problems or findings from physical examination or laboratory testing, which, in the opinion of the investigator, may pose additional risks from participation in the study, may interfere with the participant's ability to comply with study requirements or that may impact the quality or interpretation of the data obtained from the study.