Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes

Launched by MAYO CLINIC · May 2, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes," is studying how certain substances in the blood relate to diabetes and obesity. Researchers want to understand why some people have difficulties managing their blood sugar and how these issues improve after weight-loss surgery, known as bariatric surgery. By collecting blood samples before and after the surgery, the team hopes to uncover important information that could help treat diabetes more effectively.

To participate in this study, you should be enrolled in a bariatric surgery program and have a blood sugar level (A1c) of 6.5 or higher in the last six months, or have been diagnosed with stable type 2 diabetes for over six months with an A1c of less than 6.5. Unfortunately, if you are not eligible for bariatric surgery or have a body mass index (BMI) below 35, you would not qualify for this trial. If you join, you'll provide blood samples at different times, helping researchers learn more about the links between obesity and diabetes, which could lead to better treatments in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Enrolled in the Bariatric Surgery Program.
• • Patients with A1c of 6.5 or higher within the last 6 months. OR
• • Patients with A1c less than 6.5; have diagnosis of stable type 2 diabetes for \> 6 months.
• Exclusion Criteria:
• • Disqualified for Bariatric Surgery.
• • BMI \< 35 kg/m\^2.