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Search / Trial NCT06403150

The Efficacy and Safety of Levetiracetam Versus Fosphenytoin in Convulsive Status Epilepticus

Launched by DHAKA MEDICAL COLLEGE · May 6, 2024

Trial Information

Current as of July 22, 2025

Enrolling by invitation

Keywords

Status Epilepticus Levetiracetam Fosphenytoin

ClinConnect Summary

A randomized control trial will be conducted in the Department of Neurology, DMCH. Ethical approval will be obtained from the DMCH ethical review board before the study. After the selection of the subjects, the nature, purpose, and benefit of the study will be explained to each subject \& their legal attendants in detail. They will be encouraged for voluntary participation. Informed written consent will be taken from the participants or their legal attendants. Diagnosis of Status epilepticus will be made according to the criteria of the ILAE task force on classification of status epilepticu...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age \>18 years
  • Patients with convulsive status epilepticus
  • Both male and female
  • Willing to give consent
  • Exclusion Criteria:
  • Patients with convulsive status epilepticus already intubated before treatment
  • Acute precipitant of seizure was major trauma, hypoglycemia, hyperglycemia, cardiac arrest, or post-anoxia
  • Known allergic to FPHT or LEV
  • Pregnant patient
  • Liver disease or severe renal impairment

About Dhaka Medical College

Dhaka Medical College is a prestigious medical institution in Bangladesh, renowned for its commitment to advancing healthcare through rigorous research and clinical education. As a clinical trial sponsor, Dhaka Medical College provides a robust framework for conducting innovative research aimed at improving patient outcomes and enhancing medical knowledge. The institution is dedicated to upholding the highest ethical standards in clinical trials, ensuring participant safety, and fostering collaborations with local and international research entities. With a focus on evidence-based medicine, Dhaka Medical College actively contributes to the development of new therapies and treatment protocols, positioning itself as a leader in the medical research community.

Locations

Dhaka, , Bangladesh

Patients applied

0 patients applied

Trial Officials

Dr Md Amirul Islam, MBBS

Principal Investigator

MD (Neurology) Phase B Resident

Professor Dr Kazi Gias Uddin Ahmed, MD

Study Chair

Professor of Neurology, Dhaka Medical College

Dr Reaz Mahmud, MD

Study Director

Assistant Professor of Neurology, Dhaka Medical College

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported