Transcutaneous Vagus Nerve Stimulation in Aphasia After Stroke

Launched by SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST · May 3, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new technique called Transcutaneous Vagus Nerve Stimulation (tVNS) to help people recover their language skills after a stroke. Aphasia, a common condition following a stroke, makes it hard for individuals to find and use words, affecting about 30% of stroke survivors. The study aims to see if combining tVNS with computer-based Speech and Language Therapy (SLT) can improve word-finding abilities in people who have had a stroke more than six months ago and are facing challenges with language.

To participate, individuals must have had a stroke affecting their language skills and be able to use the program with some support if needed. Unfortunately, those with certain medical devices, currently receiving SLT, or who have specific health conditions cannot join. Participants will use a small device at home for six weeks while engaging in computer-based therapy. This study is not yet recruiting, but it could lead to larger trials in the future if it shows promise.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Supratentorial stroke at least 6 months prior to recruitment
• • Aphasia (with word finding difficulties)
• • Ability to engage in the programme (support can be provided for cognitive or receptive difficulties)
• • Sufficient vision to engage in the computer-based SLT programme
• Exclusion Criteria:
• • Implanted devices (e.g. pacemaker) or implanted stimulation devices
• • Currently receiving a programme of Speech and Language Therapy (SLT)
• • Damage to the vagus nerve
• • Symptomatic bradycardia/ 2nd or 3rd heart block
• • Pregnancy
• • Unable to speak English
• • Severe deafness (despite using hear aids)