Gastric Emptying After Sleeve Gastrectomy
Launched by RIJNSTATE HOSPITAL · May 6, 2024
Trial Information
Current as of June 12, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how quickly food leaves the stomach after a type of weight loss surgery called sleeve gastrectomy. The goal is to understand why some women lose a lot of weight after the surgery (more than 35% of their total weight) while others lose less (less than 25%). Researchers will use special imaging techniques, like scintigraphy and MRI, to measure gastric emptying, which is how fast the stomach empties its contents into the intestines. By comparing these two groups, the study hopes to learn more about how the surgery affects weight loss.
To participate, women aged 20 to 55 who had sleeve gastrectomy at least 2-3 years ago may be eligible, depending on their weight loss results. However, certain conditions might exclude someone, such as having a high body mass index (BMI over 50), certain medical issues affecting appetite or digestion, or being pregnant or breastfeeding. If eligible, participants can expect to undergo tests that will help researchers learn more about the effects of the surgery on their gastric emptying, ultimately contributing to better understanding and support for patients after sleeve gastrectomy.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Women aged between 20 and 55 years who underwent sleeve gastrectomy as primary procedure with either TWL \< 25% or TWL \> 35%.
- • Patients who had a follow-up period of 2-3 years after sleeve gastrectomy
- Exclusion Criteria:
- • Maximum BMI \>50 kg/m2
- • Patients with a disease known to affect appetite, gastric emptying or gastrointestinal motility
- • Patients who are unable to stop medications that affect gastric emptying and/or motility prior to measurements. It is depending on t1/2 for how long they need to stop medication
- • Patients who started menopause
- • Patients with gastrointestinal problems or, gastric or intestinal diseases
- • Patients with a drug or alcohol addiction
- • Patients who are unable to stop smoking for 24h
- • Patients who are pregnant or lactating
- • Patients who have an intolerance or allergy for one of the components of the test product
- • Patients who have a contra-indication to MRI scanning
About Rijnstate Hospital
Rijnstate Hospital is a leading healthcare institution based in the Netherlands, dedicated to providing high-quality patient care and advancing medical research. With a strong emphasis on innovation and collaboration, Rijnstate Hospital actively engages in clinical trials to explore new treatment options and improve patient outcomes across various medical fields. The hospital's multidisciplinary approach integrates the expertise of healthcare professionals, researchers, and academic partners, ensuring rigorous scientific methodologies and adherence to ethical standards. Committed to enhancing the health and well-being of the communities it serves, Rijnstate Hospital plays a pivotal role in the advancement of medical knowledge and the development of effective therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Arnhem, Gelderland, Netherlands
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported