Pulmonary Ventilation Heterogeneity Determined by EIT During PFT in Subjects With Normal One-second Rates

Launched by SIR RUN RUN SHAW HOSPITAL · May 6, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well a new technique called Electrical Impedance Tomography (EIT) can help us understand how air moves in the lungs of people who have normal lung function based on a common test called the one-second rate. The researchers want to see if EIT can identify differences in how well different parts of the lungs are working during standard lung function tests. This information could be valuable for early detection and monitoring of lung issues, even when the one-second rate appears normal.

To participate in this study, you need to be at least 18 years old and have been advised by your doctor to undergo lung function tests. However, if you have certain conditions, such as specific lung diseases, recent serious heart problems, or medical devices like pacemakers that might interfere with testing, you may not be eligible. Participants can expect to take part in lung function tests and EIT assessments, with the aim of contributing to better understanding and treatment of lung health in the future. It’s important to know that the study is currently recruiting participants of all genders and aims to gather a diverse group of individuals.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years old. Patients who need to complete lung function tests assessed by outpatient physicians.
• • Patients willing to participate in the study and sign an informed consent form.
• Exclusion Criteria:
• • Patients with FEV1/FVC less than 0.7 after a bronchiectasis test. Patients with a history of lung diseases other than COPD, previous lung surgery, or radiation therapy.
• • Patients who cannot be evaluated for EIT or who interfere with EIT results, such as implanted pacemakers/cardioverters.
• • Patients who cannot complete EIT or may interfere with EIT results, such as those with implanted pacemakers/defibrillators.
• • Patients who cannot complete lung function tests, such as myocardial infarction or shock in the past 3 months; severe heart failure or angina in the past 4 weeks，uncontrolled hypertension (systolic \>200mmHg, diastolic \>100mmHg)，severe hyperthyroidism etc.
• • Vulnerable populations, including patients with mental illnesses, cognitive impairments, critically ill patients, illiterate, pregnant women, etc.