Tumor Cell Plasticity and Aggressiveness in Human Non-small Cell Lung Cancer

Launched by CASA SOLLIEVO DELLA SOFFERENZA IRCCS · May 7, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating how certain cancer cells in lung adenocarcinoma, the most common type of lung cancer, can change and become more aggressive. Researchers want to understand the biological processes that allow these cells to behave like stem cells, which can lead to more severe disease and a higher chance of spreading (metastasis). They have already found specific markers that can help identify aggressive cases of lung adenocarcinoma at an early stage, and they hope to uncover more information that could lead to better treatment options for patients.

To participate in this trial, you need to be diagnosed with lung adenocarcinoma and have not received any prior treatment, such as chemotherapy or radiation. You should also be planning to undergo surgery as part of your care. If you join the study, researchers will analyze your tumor cells to learn more about their characteristics at a detailed level. This information may help improve how aggressive lung adenocarcinoma is managed in the future. The trial is not yet recruiting participants, but it aims to gather insights that could make a difference in lung cancer treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients diagnosed with lung adenocarcinoma
• • treatment naive
• • undergoing primary surgery
• Exclusion Criteria:
• • patients with a previous history of cancer
• • previously treated by chemio/immuno/radio-therapy