MUSCLE EFFECTS OF NEUROMUSCULAR ELECTROSTIMULATION IN MECHANICALLY VENTILATED PATIENTS IN AN ICU

Launched by UNIVERSIDADE FEDERAL DO RIO DE JANEIRO · May 7, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how neuromuscular electrical stimulation (NMES) can help prevent muscle weakness in patients who are on mechanical ventilation in the Intensive Care Unit (ICU). Muscle weakness, known as ICU-acquired weakness, can happen when patients are unable to move for long periods. The researchers want to see if using NMES for at least 10 days can help maintain muscle strength and quality in these patients. They will also use ultrasound to assess the condition of the muscles, specifically focusing on the quadriceps, which are important for movement.

To participate in the trial, you must be at least 18 years old and have been on mechanical ventilation for less than 24 hours. You will need to give consent, or your family member can do it for you. However, there are certain conditions that may exclude someone from joining, such as having a recent injury to the legs or a history of serious neurological issues. If you are eligible and decide to participate, you will be randomly assigned to either receive NMES treatment or be in a control group that does not receive the treatment. This trial is not yet recruiting participants, but it aims to shed light on important ways to support muscle health in critically ill patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥18 years;
• • 2. On mechanical ventilation in the first 24 hours;
• • 3. Provision of written, informed and/or agreed consent for a family member.
• Exclusion Criteria:
• • 1. Trauma to the lower limb;
• • 2. History of neurological, neuromuscular or debilitating diseases;
• • 3. Spinal cord injury;
• • 4. Rhabdomyolysis;
• • 5. Vascular insufficiency or amputation of the lower limb;
• • 6. Previous immobility;
• • 7. Epilepsy;
• • 8. Musculoskeletal and skin conditions or situations that may interfere in conduct.