Electrocorticographic Monitoring of Brain Retraction Injury (EMBRI)

Launched by UNIVERSITY COLLEGE, LONDON · May 7, 2024

Keywords

ClinConnect Summary

The Electrocorticographic Monitoring of Brain Retraction Injury (EMBRI) trial is studying a new way to monitor the brain during surgery, specifically looking for signs of brain injury that might occur when the brain is gently moved or retracted. This is the first time this technique is being tested in humans, following promising results from earlier experiments on mice. The goal is to improve safety and outcomes for patients undergoing neurosurgery.

To be eligible for this trial, participants need to be at least 16 years old and scheduled for surgery that requires the brain to be temporarily moved. During the surgery, in addition to standard monitoring, a special electrode will be placed on the brain to help doctors watch for any signs of injury caused by the retraction. Patients can expect to undergo their usual surgical procedure while contributing to important research that could benefit future patients. It's important to note that patients who are unable to give consent at the time of recruitment will not be able to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 16 or older undergoing intracranial surgery where it is anticipated fixed brain retraction will be used.
• Exclusion Criteria:
• • Patients without capacity to give consent at time of recruitment