Predictive Models for the Treatment of Recurrent Herpes Zoster Neuralgia Following Spinal Cord Electrical Stimulation.

Launched by FENG GAO · May 9, 2024

Keywords

ClinConnect Summary

Shingles is a neuropathic disease caused by varicella-herpes virus(VZV) invading nerves and accompanying pain. About 3\~5/1000 people suffer from shingles every year in the world, and 2.9\~5.8/1000 people over the age of 50 in China suffer from shingles every year, with an annual growth rate of 2.5\~5.0%. If acute herpes zoster can not be treated effectively, it will be transformed into postherpetic neuralgia (PHN), patients will suffer long-term knife, needle, burning pain as well as hyperalgesia, touch induced pain and skin paresthesia, which seriously affect the daily life of patients. I...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years old.
• • NRS score ≥4 points.
• • The pain NRS of previous shingles area treated with SCS was ≤3, and the pain NRS was \> 4 after recurrence.
• Exclusion Criteria:
• • Serious cardiovascular and cerebrovascular diseases, such as heart failure, intracranial aneurysm, hypertension (high risk, very high risk).
• • Epilepsy, suffering from mental illness.
• • And patients who were lost to follow-up.