Ejaculation Abstinence Time and Assisted Reproductive Technology Outcomes

Launched by THE FIRST HOSPITAL OF JILIN UNIVERSITY · May 7, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating whether reducing the time a man abstains from ejaculation can improve the success of assisted reproductive technologies, like in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). The researchers want to find out if having less than 48 hours of abstinence before providing a sperm sample leads to better pregnancy rates, healthier embryos, and lower chances of pregnancy loss compared to abstaining for 3 to 7 days.

To participate, couples need to be between 20 and 45 years old, and the woman should have a healthy body weight. The man must have normal ejaculation and be willing to provide a sperm sample on the day the eggs are retrieved. However, couples with serious health issues, certain fertility problems, or specific conditions affecting sperm quality may not be eligible. Participants will be monitored to see how these different abstinence times impact their IVF outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The couple is between 20 and 45 years old, and the woman's body mass index is greater than 18.5 and less than 30kg/m2.
• • Meet the indications of assisted reproductive technology, agree to use assisted reproductive technology to assist pregnancy and have entered the process.
• • The male has normal ejaculation function and plans to provide a semen sample by masturbation method on the day of egg retrieval.
• Exclusion Criteria:
• • Couples with serious infections and major physical diseases, such as HIV.
• • The use of testicular sperm for intracytoplasmic sperm injection, such as the azoospermia.
• • The use of frozen sperm for assisted reproductive technology.
• • Endometriosis, repeated implantation failure, etc.
• • There are clear factors affecting semen parameters within 3 months before sperm extraction, including high temperature, contact with chemicals，radiation or drugs that affect sperm, etc.;Previous orchitis/epididymitis, cryptorchidism, receiving radiotherapy and chemotherapy treatment