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Search / Trial NCT06415825

Preliminary Muscle Contraction in the Rehabilitation and Prevention of Degenerative Pain in the Locomotor System

Launched by MEDICAL UNIVERSITY OF SOFIA · May 14, 2024

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Degenerative Pain Spine Hip Knee Ankle Shoulder Elbow Hip And Knee Arthroplasty

ClinConnect Summary

This clinical trial is investigating a new approach to help people with chronic joint pain, especially in areas like the back, hips, knees, shoulders, and elbows. The researchers want to see if a technique called "preliminary muscle contraction" can improve rehabilitation and prevent future pain after surgeries like hip or knee replacements. The study will involve at least 216 participants who have experienced ongoing pain in these areas and will look at their pain levels and muscle strength over six months.

To be eligible for this trial, participants need to be over 18 years old and have had recurrent joint pain, with at least two flare-ups in the past year. They should be experiencing pain but not have any severe neurological issues or major injuries. Participants will receive standard advice on managing their pain, and those in the muscle contraction group will learn how to incorporate this technique into their daily activities. The hope is that this simple, quick exercise can be easily added to everyday life, helping to reduce pain and improve function without requiring extra time or resources.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age over 18 years;
  • legal capacity;
  • patients with recurrent degenerative pain (at least two relapses in the last 12 months), in various joints (vertebral, hip, knee, ankle, shoulder, elbow, and knee), in an exacerbation stage (started up to 2 weeks before recruitment), occurring with periodic exacerbations and remissions (relapse duration of more than 24 hours, preceded and separated by remission of at least 1 month);
  • with excitatory (painful) symptoms (but without ablated ones - without paresis, paralysis, and pelvic-reservoir damage);
  • as well as after hip and knee arthroplasty.
  • Exclusion Criteria:
  • age under 18,
  • incapacity;
  • neurological symptoms have disappeared (paresis, paralysis, and pelvic-reservoir disorders),
  • macro-injuries (fractures, dislocations, distortions),
  • structural anomalies, severe osteoporosis, infectious diseases, febrility, malignant diseases, specific inflammatory and autoimmune diseases (such as rheumatoid arthritis, ankylosing spondylarthritis, etc.), mental diseases, increased tendency to bleed (hemophilia, etc.), as well as cardiovascular vascular, respiratory, liver, kidney and metabolic damage with marked failure.

About Medical University Of Sofia

The Medical University of Sofia is a prestigious academic institution dedicated to advancing healthcare through innovative research and clinical trials. Renowned for its commitment to excellence in medical education, the university fosters a collaborative environment that integrates scientific inquiry with practical application. As a clinical trial sponsor, the Medical University of Sofia prioritizes patient safety and ethical standards, while aiming to contribute valuable insights to the medical community. Through rigorous study design and multidisciplinary expertise, the university seeks to enhance treatment options and improve health outcomes across diverse populations.

Locations

Patients applied

0 patients applied

Trial Officials

Assen R Aleksiev

Principal Investigator

Head Department of Physical Medicne and Rehabilitation, Medical University of Sofia

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported