Non-invasive BCI and Application Verification for Depressed People

Launched by SHANGHAI MENTAL HEALTH CENTER · May 12, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating new ways to help people with depression, including Major Depressive Disorder (MDD) and Bipolar Depression. Researchers are looking to develop two types of non-invasive brain-computer interface (BCI) systems that can help regulate emotions. One system will be used in hospitals for precise treatment, while the other will also be suitable for home use. The goal is to gather information from people with depression and healthy individuals to better understand the brain's responses and create effective emotional support tools, including interactive games designed to help with depression.

To participate in this study, you need to be at least 12 years old and meet specific criteria, such as being diagnosed with depression according to standard guidelines. Certain health conditions, like severe brain injuries or specific mental health disorders, may prevent you from participating. If you join the study, you can expect to undergo various assessments and contribute to developing new technology aimed at improving treatment for depression. Your involvement could help pave the way for better, more personalized interventions for those affected by this serious condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ≥ 12 years old, male or female, right-handed, Han ethnicity
• • Meets the DSM-5 diagnostic criteria for depression, with HAMD-17 scores greater than 17 and YMRS scores less than 6;
• • Primary school education or above, able to understand the research content, willing to participate in this study and sign an informed consent form
• Exclusion Criteria:
• • Concomitant or previous history of organic brain disease or severe traumatic brain injury, personal or family history of epilepsy;
• • Severe abnormalities in heart, liver, and kidney function;
• • Patients with severe physical illnesses;
• • History of substance dependence or abuse (alcohol, cocaine, drugs, etc.);
• • Patients with mental disorders caused by organic diseases, drug or alcohol induced mental disorders, and other mental disorders;
• • Pregnancy or lactation period;
• • Within six months, physical therapy such as MECT and TMS should be used;
• • Implants of vegetative nerve stimulation;
• • Individuals who have implanted electronic or metal instruments (such as pacemakers, defibrillators, stents, orthopedic plates, etc.) and undergo ventriculoperitoneal shunt surgery;
• • Obvious visual and auditory impairment, unable to cooperate in completing neuropsychological and scale assessments.

Trial Officials