Trials
Search / Trial NCT06418308

Intrathecal Dexmedetomidine Vs Epinephrine

Launched by ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · May 13, 2024

Trial Information

Current as of February 19, 2025

Recruiting

Keywords

Cesarean Section Spinal Anesthesia Intrathecal Adjuncts Dexmedetomidine Epinephrine

ClinConnect Summary

This clinical trial is studying the effects of two different medications, dexmedetomidine and epinephrine, when added to spinal anesthesia for women undergoing cesarean sections. The aim is to find out if dexmedetomidine works just as well as epinephrine in providing pain relief during and after the surgery, without causing more side effects. Both medications have been shown in previous studies to help with pain management, but this is the first study to directly compare them.

To participate in this trial, women aged 18 to 55 who are pregnant and scheduled for a planned cesarean section may be eligible. However, those who have certain medical conditions, like severe bleeding disorders or infections at the injection site, or who are having an emergency cesarean section, will not be able to join. Participants can expect to receive either dexmedetomidine or epinephrine during their spinal anesthesia, and the researchers will monitor their pain levels and any side effects following the procedure. This study is important because it aims to discover the best way to manage pain for women during cesarean deliveries.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Pregnant patients
  • aged 18-55 years
  • presenting for scheduled primary or secondary cesarean section
  • candidates for single shot spinal anesthesia singleton pregnancy
  • Exclusion Criteria:
  • patient refusal of spinal anesthetic
  • if patient is not a candidate for spinal anesthesia due to history of coagulopathy, elevated intracranial pressure, infection at site of injection, etc.
  • emergency cesarean section
  • preexisting motor or sensory deficit
  • suspected pre-eclampsia
  • patient receiving combined spinal-epidural as anesthetic technique
  • BMI \> 40

Trial Officials

Daniel Katz, MD

Principal Investigator

Icahn School of Medicine at Mount Sinai

About Icahn School Of Medicine At Mount Sinai

The Icahn School of Medicine at Mount Sinai is a premier academic institution located in New York City, renowned for its commitment to advancing medical research, education, and patient care. As a leading sponsor of clinical trials, the institution leverages its state-of-the-art facilities and multidisciplinary expertise to drive innovative research initiatives aimed at improving health outcomes. With a focus on translational medicine, the Icahn School of Medicine collaborates with a diverse network of researchers, clinicians, and industry partners to explore novel therapies and interventions across a wide range of medical disciplines. Its rigorous scientific approach and dedication to ethical standards position it as a trusted leader in the clinical research landscape.

Locations

New York, New York, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0