Intrathecal Dexmedetomidine Vs Epinephrine

Launched by ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · May 13, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of two different medications, dexmedetomidine and epinephrine, when added to spinal anesthesia for women undergoing cesarean sections. The aim is to find out if dexmedetomidine works just as well as epinephrine in providing pain relief during and after the surgery, without causing more side effects. Both medications have been shown in previous studies to help with pain management, but this is the first study to directly compare them.

To participate in this trial, women aged 18 to 55 who are pregnant and scheduled for a planned cesarean section may be eligible. However, those who have certain medical conditions, like severe bleeding disorders or infections at the injection site, or who are having an emergency cesarean section, will not be able to join. Participants can expect to receive either dexmedetomidine or epinephrine during their spinal anesthesia, and the researchers will monitor their pain levels and any side effects following the procedure. This study is important because it aims to discover the best way to manage pain for women during cesarean deliveries.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Pregnant patients
• • aged 18-55 years
• • presenting for scheduled primary or secondary cesarean section
• • candidates for single shot spinal anesthesia singleton pregnancy
• Exclusion Criteria:
• • patient refusal of spinal anesthetic
• • if patient is not a candidate for spinal anesthesia due to history of coagulopathy, elevated intracranial pressure, infection at site of injection, etc.
• • emergency cesarean section
• • preexisting motor or sensory deficit
• • suspected pre-eclampsia
• • patient receiving combined spinal-epidural as anesthetic technique
• • BMI \> 40

Trial Officials