Trials
Search / Trial NCT06418438

A Randomized Controlled Trail of Uterosacral Ligament Suspension in the Treatment of Pelvic Organ Prolapse

Launched by LAN ZHU · May 13, 2024

Trial Information

Current as of February 19, 2025

Not yet recruiting

Keywords

ClinConnect Summary

No description provided

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Age ≥ 18 years with symptomatic stage II or higher uterine prolapse (C ≥ +1cm) and gynecological ultrasonography confirming cervical length ≥ 4cm. Concurrent anterior and/or posterior vaginal wall prolapse may be present.
  • Preoperative pelvic ultrasound and cervical screening show no abnormalities.
  • The patient does not have a desire for future fertility.
  • Willingness and ability to adhere to the follow-up treatment plan.
  • Competence to provide informed consent.
  • Exclusion Criteria:
  • Suspected untreated lower genital tract tumor, accompanied by other uterine, ovarian, and cervical lesions requiring surgical intervention, indicating contraindication for uterine preservation.
  • Patients with a history of total hysterectomy/subtotal hysterectomy.
  • Patients who have previously undergone pelvic organ prolapse surgery or other pelvic floor surgeries.
  • Patients with contraindications for laparoscopic surgery, such as intestinal obstruction.
  • Patients with intestinal hernia.
  • Patients with gynecological and urinary tract infections, anticoagulant therapy, coagulation disorders, previous pelvic radiotherapy, as well as neurological or medical conditions affecting bladder and bowel function (such as multiple sclerosis, spinal cord injury, or residual neurological dysfunction caused by stroke), and patients with underlying conditions such as chronic pelvic pain, who are at higher risk for surgery.
  • Simultaneous anti-urinary incontinence surgery is required for this procedure.

Trial Officials

Lan Zhu, MD

Principal Investigator

Peking Union Medical College Hospital

About Lan Zhu

Lan Zhu is a dedicated clinical trial sponsor committed to advancing medical research and innovation. With a focus on integrity and scientific rigor, Lan Zhu collaborates with leading healthcare professionals and institutions to design and execute clinical trials that address unmet medical needs. The organization prioritizes patient safety and ethical standards, ensuring that all trials adhere to regulatory guidelines while fostering a culture of transparency and collaboration. By leveraging cutting-edge methodologies and data-driven insights, Lan Zhu aims to contribute to the development of effective therapies that enhance patient outcomes and improve public health.

Locations

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0