The Effects of Fermented Brown Seaweed Intake on Glucose Metabolism and Gut Health

Launched by AVENTURE AB · May 16, 2024

Keywords

ClinConnect Summary

Fermented seaweed is a sustainable food with increasing interest as an ingredient of a plant-based diet. Plant-based diets are gaining popularity both because of their health benefits and low-carbon footprint. Seaweed is a rich source of minerals, polyphenols and dietary fibres like xylans, carrageenan, fucoidan, laminarin and alginate. These bioactive compounds have been shown to exert positive effects on metabolic parameters, such as blood glucose and insulin, blood lipid profile and inflammatory markers and could therefore help in the prevention of cardiovascular diseases. Besides possib...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy males and females
• • Age 20-40 years, at the time of signing the informed consent
• • BMI 20-25 kg/m2
• • Stable body weight (less than 5% difference during the last 3 months)
• • Willing and able to give written informed consent for participating the study
• • Willing to comply with all study procedures
• Exclusion Criteria:
• • Intake of antibiotics within 4 weeks prior to the start of the study
• • Regular intake of probiotics and/or prebiotics within 4 weeks prior to the start of the study
• • Tobacco use (smoking and/or snus)
• • High alcohol intake: \> 4 glasses daily
• • Pregnancy or lactating
• • Chronical disease (e.g., liver, kidney)
• • Diabetes
• • Gastrointestinal disease (ulcerative colitis, Crohn's disease, irritable bowel syndrome)
• • Heart disease (within the last 12 months)
• • Inflammatory disease (e.g. asthma, GI inflammatory diseases) and auto-immune disease
• • Treatment with corticosteroids of significant degree
• • Psychological disease of significant degree
• • Cancer of significant difference
• • Gastric-bypass operation
• • Operation planned during the study period
• • Known gluten intolerance and/or lactose intolerance
• • Having allergies to the food components of the study, mustard and seafoods
• • Known gluten intolerance, lactose intolerance, milk protein allergy or other food allergies
• • Irregular diet (i.e., not eating 3 main meals daily) or special diet (e.g. vegan, low-carb high-fat, 5-2)
• • Investigator considers the subject unlikely to comply with the study procedures, restrictions, and requirements

Trial Officials