the Effects of Different Exercise on Vascular Health

Launched by CHINA NATIONAL CENTER FOR CARDIOVASCULAR DISEASES · May 14, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how different types of exercise, guided by a smart app and wearable devices, can improve vascular health, which is related to how well blood flows through your arteries. The study will specifically measure the stiffness of arterial walls, as this can be an important indicator of heart and blood vessel health. The goal is to see if using these smart devices can help manage lifestyle changes that benefit vascular health.

To participate in this trial, you need to be between 18 and 60 years old and have a specific measurement of arterial stiffness. You should also have a smartphone that you can use easily. However, there are some health conditions that would prevent you from joining, such as severe obesity, uncontrolled high blood pressure, or serious heart diseases. If you do join, you can expect to engage in various exercise routines while using the app and wearable devices to track your progress, and you'll need to provide informed consent to participate. This trial is not yet recruiting participants, so you would need to wait for the enrollment to begin.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age: ≥ 18 years old and \< 60 years old;
• • 2. cfPWV\>10m/s;
• • 3. Those who have 1 intelligent communication device and can use it proficiently (Android mobile phone is preferred);
• • 4. People who have lived and/or worked relatively steadily in the past 6 months;
• • 5. Signed informed consent.
• Exclusion Criteria:
• • 1. Moderate to severe obesity (≥30kg/m\^2);
• • 2. Acute myocardial infarction, acute tachyarrhythmia, pulmonary edema, severe aortic stenosis and other serious circulatory respiratory diseases and acute cardiovascular and cerebrovascular diseases;
• • 3. severe essential hypertension (systolic blood pressure ≥180mmHg and/or diastolic blood pressure ≥110mmHg) or poorly controlled essential hypertension;
• • 4. Patients with secondary hypertension, acute hypertension, subacute hypertension and hypertensive encephalopathy;
• • 5. Significant arrhythmia (atrial fibrillation, etc.);
• • 6. Patients with atherosclerotic cardiovascular diseases, such as coronary heart disease, severe peripheral atherosclerotic diseases, etc.;
• • 7. Type 1 diabetes, uncontrolled type 2 diabetes or other diseases affecting carbohydrate metabolism;
• • 8. Severe stenosis of the carotid and/or femoral arteries (resulting in significant abnormalities in the blood flow spectrum); Those who have anatomical abnormalities of the aorta and major branches and cannot complete PWV detection;
• • 9. Cancer and other major comorbidities affecting arterial blood pressure;
• • 10. Those who are unable to exercise due to fractures, joint instability and other physical diseases or diseases affecting the locomotor system;
• • 11. Those who have involuntary physical movements due to mental illness, epilepsy or other diseases;
• • 12. Those who have a pacemaker installed;
• • 13. Pregnant/trying to conceive;
• • 14. Patients with allergies, limb trauma or skin diseases who cannot cooperate with the completion of ABI and baPWV index examinations;
• • 15. Those who have undergone or plan to have bariatric surgery in the next 12 months;
• • 16. Those who have participated in other clinical studies in the past 3 months;
• • 17. Refusal to sign informed consent.