Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes

Launched by THOMAS JEFFERSON UNIVERSITY · May 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different ways of deciding when to start medication for gestational diabetes (GDM) affect the health of mothers and their newborns. The researchers want to compare two approaches: a strict method that requires more abnormal test results before starting treatment, and a more flexible method that allows treatment based on fewer abnormal results. By understanding how these different thresholds impact outcomes, the goal is to find the best way to manage GDM during pregnancy.

To participate in this study, you need to be a woman with a live, healthy pregnancy and able to read in English, Spanish, Mandarin, or Arabic. You must also be willing to give your consent and understand the study's purpose. If you are under 18, have diabetes before the pregnancy, are carrying more than one baby, or have certain other health issues, you may not be eligible. Participants will be closely monitored during the study, and your experiences will help improve care for future mothers with gestational diabetes.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Live, non-anomalous fetus
• • Literacy in English, Spanish, Mandarin, or Arabic
• • Patients are also required to provide consent, demonstrate an understanding of the purpose of the study, and agree to the study protocol.
• Exclusion Criteria:
• • \<18 years at EDD
• • pre-existing diabetes or diagnosis of GDM before 24 weeks
• • multi-fetal gestation
• • known major fetal anomaly
• • known allergy to insulin
• • chronic maternal corticosteroid use
• • diagnosis of GDM based on finger sticks alone
• • patients who have contraindication to oral glucose tolerance test
• • a primary language other than English, Spanish, Mandarin, or Arabic