Effects of Cerebellar tACS-iTBS in Ataxia

Launched by I.R.C.C.S. FONDAZIONE SANTA LUCIA · May 17, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to help people with ataxia, a condition that affects coordination and balance due to problems in the brain's cerebellum. Researchers want to see if a combination of two non-invasive brain stimulation techniques, called transcranial alternating current stimulation (tACS) and intermittent theta burst stimulation (iTBS), can improve balance in individuals with ataxia. Since traditional treatments haven’t been very effective for many patients, this study explores promising alternatives.

To participate in the trial, individuals need to be between the ages of 65 and 74, or 29 and 219, have a confirmed diagnosis of ataxia, and have been on stable medication for at least four weeks. Participants should also be able to understand and follow instructions. However, people with a history of seizures, certain serious health issues, or specific medical devices like metal implants or pacemakers won’t be eligible. If you qualify and choose to participate, you will likely engage in sessions involving the brain stimulation techniques being studied, with the hope of improving your coordination and balance over time.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Confirmed diagnosis of ataxia based on clinical assessment and/or neuroimaging findings.
• • 2. Stable medication regimen for at least four weeks prior to the study.
• • 3. Sufficient cognitive ability to understand and comply with study instructions.
• Exclusion Criteria:
• • 1. History of seizures.
• • 2. Severe general impairment or concomitant diseases.
• • 3. Intracranial metal implants.
• • 4. Cardiac pacemaker.
• • 5. Pregnancy status.