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Search / Trial NCT06421012

Preoxygenation for Tracheal Aspirations in Intensive Care

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · May 15, 2024

Trial Information

Current as of July 06, 2025

Recruiting

Keywords

Endotracheal Suctioning Preoxygenation Ventilation Icu

ClinConnect Summary

This clinical trial is studying the effects of a procedure called preoxygenation in patients in the Intensive Care Unit (ICU) who are on mechanical ventilation. When patients need their airways cleared of mucus or other blockages, a procedure called suctioning is performed. The trial aims to find out if giving extra oxygen for a few minutes before suctioning can help prevent problems like low oxygen levels in the blood, which can happen during the procedure. Although previous guidelines suggested preoxygenation to avoid these issues, it’s unclear if this is still necessary since suctioning is now done based on the patient's needs rather than on a regular schedule.

To participate in this trial, individuals must be 18 years or older, currently hospitalized in the ICU, and have been on mechanical ventilation for less than 24 hours. Participants will need to provide consent, either themselves or through a trusted person. The trial is currently recruiting and is open to all genders. It's important to know that while preoxygenation might reduce short-term risks of low oxygen levels, it could also lead to other complications. The trial aims to better understand these risks and benefits to improve care for ICU patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 18 years of age or older
  • Hospitalized in ICU, under invasive mechanical ventilation for less than 24 hours
  • Information and signature of consent by patient or relative/trusted person, or emergency inclusion procedure
  • Exclusion Criteria:
  • Patient on ECMO
  • Not affiliated to a social security system
  • Pregnant
  • Under legal protection (curatorship, guardianship or safeguard of justice)
  • Patient under AME
  • Patient included in another interventional study that may have an impact on the evaluation criteria of the present study

About Assistance Publique Hôpitaux De Paris

Assistance Publique - Hôpitaux de Paris (AP-HP) is a leading public hospital system in France, renowned for its commitment to healthcare excellence and innovative medical research. As a prominent clinical trial sponsor, AP-HP plays a pivotal role in advancing medical knowledge and improving patient care through rigorous scientific investigations across a wide range of therapeutic areas. With a focus on collaboration and interdisciplinary approaches, AP-HP leverages its extensive network of hospitals and expert clinicians to facilitate high-quality clinical trials that adhere to the highest ethical and regulatory standards, ultimately aiming to translate research findings into tangible health benefits for diverse patient populations.

Locations

Paris, , France

Patients applied

0 patients applied

Trial Officials

Claire FAZILLEAU

Principal Investigator

Hôpital Pitié Salpêtrière - Assistance Publique Hôpitaux de Paris

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported