Transcutaneous Auricular Vagus Nerve Stimulation Prevents Postoperative Delirium in Elderly Patients

Launched by BEIJING TIANTAN HOSPITAL · May 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a treatment called Transauricular Vagus Nerve Stimulation (taVNS) on elderly patients who have just had surgery. The goal is to see if this treatment can help prevent a condition known as postoperative delirium, which is confusion and disorientation that can occur after surgery. Researchers want to find out how effective and safe this treatment is for improving brain health in older adults after they undergo surgery.

To be eligible for this trial, participants should be at least 65 years old, have a scheduled surgery that will last at least 2 hours, and expect to stay in the hospital for at least 4 days afterward. Those who have had certain types of surgeries, like brain or heart surgery, or have serious existing health issues may not qualify. If chosen to participate, patients can expect to receive the taVNS treatment and will be monitored for signs of delirium during their recovery. This study is important because it could lead to new ways to protect the brain health of older patients after surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age≥65 years
• • Expected operation time≥ 2 hours
• • Postoperative hospital stay≥ 4 days
• • Sign the informed consent form
• Exclusion Criteria:
• • Neurosurgery or cardiac surgery
• • Emergency surgery within 6 hours of admission
• • End-stage disease with an expected survival of \< 3 months
• • Preoperative severe cognitive dysfunction affected perioperative cognitive function assessment
• • Severe sinus bradycardia, AVB of degree II and above, pacemaker placement