Efficiency of Spatially Distributed Sequential Stimulation (Sdss) for Functional Electrical Stimulation (FES) of Upper Motor Neuron Syndrome (UMR) Patients

Launched by UGECAM RHÔNE-ALPES · May 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new method called Spatially Distributed Sequential Stimulation (Sdss) to see if it is more effective than the standard electrical stimulation used for patients with Upper Motor Neuron Syndrome (UMR). UMR patients often experience weakness in their muscles due to conditions affecting the brain and spinal cord. The goal of the trial is to find out if this new stimulation method can better help improve muscle function and movement for these patients.

To participate in this trial, individuals need to be adults over 18 years old who have muscle weakness from an injury or disease affecting their nervous system. They should be in a stable health condition, especially regarding their heart, and should be able to tolerate electrical stimulation without any issues. Participants will be expected to complete cycling exercises for about 30 minutes using the stimulation method being tested. It's important to note that those with certain heart conditions, severe cognitive issues, or who are currently pregnant cannot join the study. If eligible, participants will have a chance to contribute to important research that could improve treatments for muscle weakness in UMR patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Patients with Upper Motor Neuron syndrome:
• • adult (\> 18 years)
• • motor deficit due to an acquired traumatic or neurodegenerative motor deficiency of the central nervous system (MRC\<4/5)
• • stable clinical condition, particularly on the cardiovascular level (recent assessment by a cardiologist with stress test)
• • non denervated muscles
• • tolerant to muscle electrical stimulation
• • having given written consent
• • able to cycle 30 minutes with FES-cycling
• Exclusion Criteria:
• • major cognitive comprehension disorders that could compromise understanding of the protocol and the smooth running of the study
• • cardiac pacemaker and other contraindications relating to the use of electrostimulation (in particularly "deep vein thrombosis")
• • spasticity of the lower limbs making flexion/extension movement difficult
• • participation in another study
• • pregnancy
• * people with the following legal and administrative states or situations:
• • people placed under judicial protection;
• • persons deprived of their liberty, persons subject to psychiatric care and persons admitted to a health or social establishment for purposes other than that of clinical investigation;
• • unemancipated minors;
• • people who are not affiliated to a social security scheme or beneficiaries of such a scheme