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Search / Trial NCT06421922

Effect of Different Dietary Therapies on Intestinal Barrier Integrity in Patients With Irritable Bowel Syndrome

Launched by GULHANE TRAINING AND RESEARCH HOSPITAL · May 14, 2024

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Trial Information

Current as of March 14, 2025

Completed

Keywords

ClinConnect Summary

This was a non-pharmacological randomized controlled trial conducted at Ankara Gülhane Training and Research Hospital Gastroenterology Polyclinic between June 2019 and March 2020. Participants of this study were women aged 19 to 50 years with a diagnosis of IBS according to the Rome IV criteria (2017).

The sample size was calculated with G\*Power software. With an estimated power of 90%, a Type I error of 0.05, and an effect size of f=0.25, the total sample size required was 54, consisting of 18 participants in each group. The sample size was calculated using G\*Power software. The total s...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • • Women aged 19-50 years who were diagnosed with IBS according to Rome IV criteria
  • • Any metabolic disease (diabetes, heart disease, etc.), cancer and autoimmune no history of chronic diseases such as illness
  • • Not being pregnant or lactating
  • • Body mass index (BMI) of 18.5-29.9 kg/m2
  • Exclusion Criteria:
  • • Chronic disease history such as cancer and autoimmune diseases
  • • Probiotics use or nutritional supplement use (vitamins, minerals) in the last 6 months.
  • • Pregnancy.

Trial Officials

Emine Nuket Unsal, Phd

Principal Investigator

Gulhane Training and Research Hospital

About Gulhane Training And Research Hospital

Gulhane Training and Research Hospital is a leading healthcare institution dedicated to advancing medical knowledge and patient care through innovative clinical research. Located in Turkey, the hospital serves as a prominent center for training healthcare professionals and conducting rigorous clinical trials across various medical fields. With a commitment to excellence, Gulhane integrates cutting-edge technology and evidence-based practices to enhance therapeutic outcomes and contribute to the global medical community. The hospital's collaborative approach fosters partnerships with academic institutions and industry leaders, ensuring the highest standards of ethical conduct and scientific integrity in all research endeavors.

Locations

Ankara, Keçiören, Turkey

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0