Epidemiological Investigation of Helicobacter Pylori-infected Patients and the Effect of Eradication Treatment on Dyspepsia Symptoms
Launched by SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE · May 14, 2024
Trial Information
Current as of February 08, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how many people with a Helicobacter pylori (H. pylori) infection experience symptoms of dyspepsia, which is a term used to describe discomfort in the upper stomach, including feelings of fullness, nausea, or heartburn. The study will also monitor how these symptoms improve after treating the infection. The goal is to gather information that can help doctors better understand and treat patients who have H. pylori infections along with dyspeptic symptoms.
To participate in the study, you need to be between the ages of 18 and 80 and have a confirmed H. pylori infection. You cannot have any serious digestive diseases or other significant health issues, and women who are pregnant or breastfeeding are not eligible. If you join the study, you can expect regular follow-up visits to check on your symptoms and how well the treatment is working. This research aims to improve treatment options for people suffering from the discomfort caused by H. pylori infections.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Male or female patients aged 18-80 years
- • H. pylori infection diagnosed by 13C/ 14C-UBT (\> 2 times the cutoff value) and/or gastroscopy (rapid urease strong positive and histological positive)
- • Treatment-naive patients with Helicobacter pylori
- • Ability and willingness to participate in the study and to sign and give informed consent
- Exclusion Criteria:
- • Under 18 or over 80 years old
- • Organic digestive diseases, such as active peptic ulcer, gastroesophageal reflux, gastrointestinal bleeding, acute/chronic pancreatitis, acute/chronic cholecystitis, gallstones, intestinal obstruction, inflammatory bowel disease, etc.
- • Combined with melena, hematemesis, anemia, emaciation and other alarm symptoms
- • Pregnant and lactating women
- • History of cancer
- • History of subtotal gastrectomy
- • Severe organ dysfunction of heart, liver, kidney, lung and other important organs and congenital diseases, such as grade IV heart failure, liver failure, uremia, respiratory failure, hemophilia, Wilson's disease, etc.
About Shanghai Jiao Tong University School Of Medicine
Shanghai Jiao Tong University School of Medicine is a leading academic institution in China, renowned for its commitment to advancing medical research and education. As a prominent clinical trial sponsor, the school leverages its extensive expertise in biomedical sciences and innovative healthcare solutions to conduct rigorous clinical studies aimed at improving patient outcomes. With a focus on collaboration and translational research, the institution fosters partnerships with healthcare providers, industry leaders, and regulatory bodies to ensure the highest standards of scientific integrity and ethical conduct in clinical trials. Through its research initiatives, Shanghai Jiao Tong University School of Medicine strives to contribute significantly to the global medical community and enhance the quality of healthcare delivery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Xiamen, Fujian, China
Baotou, Inner Mongolia, China
Dalian, Liaoning, China
Xuchang, Henan, China
Shanghai, Shanghai, China
Wuhan, Hubei, China
Luoyang, Henan, China
Shanghai, Shanghai, China
Chongqing, Chongqing, China
Dalian, Liaoning, China
Chongqing, Chongqing, China
Wuwei, Gansu, China
Qinzhou, Guangxi, China
Shanghai, Shanghai, China
Chengdu, Sichuan, China
Kashgar, Xinjiang, China
Kunming, Yunnan, China
Ningbo, Zhejiang, China
Ningbo, Zhejiang, China
Chongqing, Chongqing, China
Shangqiu, Henan, China
Dalian, Shandong, China
Shanghai, Shanghai, China
Shanghai, Shanghai, China
Tianjing, Tianjing, China
Shaoxing, Zhejiang, China
Shanghai, Shanghai, China
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0