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Epidemiological Investigation of Helicobacter Pylori-infected Patients and the Effect of Eradication Treatment on Dyspepsia Symptoms

Launched by SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE · May 14, 2024

Trial Information

Current as of February 08, 2025

Recruiting

Keywords

Helicobacter Pylori Infection Dyspepsia

ClinConnect Summary

This clinical trial is looking at how many people with a Helicobacter pylori (H. pylori) infection experience symptoms of dyspepsia, which is a term used to describe discomfort in the upper stomach, including feelings of fullness, nausea, or heartburn. The study will also monitor how these symptoms improve after treating the infection. The goal is to gather information that can help doctors better understand and treat patients who have H. pylori infections along with dyspeptic symptoms.

To participate in the study, you need to be between the ages of 18 and 80 and have a confirmed H. pylori infection. You cannot have any serious digestive diseases or other significant health issues, and women who are pregnant or breastfeeding are not eligible. If you join the study, you can expect regular follow-up visits to check on your symptoms and how well the treatment is working. This research aims to improve treatment options for people suffering from the discomfort caused by H. pylori infections.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Male or female patients aged 18-80 years
  • H. pylori infection diagnosed by 13C/ 14C-UBT (\> 2 times the cutoff value) and/or gastroscopy (rapid urease strong positive and histological positive)
  • Treatment-naive patients with Helicobacter pylori
  • Ability and willingness to participate in the study and to sign and give informed consent
  • Exclusion Criteria:
  • Under 18 or over 80 years old
  • Organic digestive diseases, such as active peptic ulcer, gastroesophageal reflux, gastrointestinal bleeding, acute/chronic pancreatitis, acute/chronic cholecystitis, gallstones, intestinal obstruction, inflammatory bowel disease, etc.
  • Combined with melena, hematemesis, anemia, emaciation and other alarm symptoms
  • Pregnant and lactating women
  • History of cancer
  • History of subtotal gastrectomy
  • Severe organ dysfunction of heart, liver, kidney, lung and other important organs and congenital diseases, such as grade IV heart failure, liver failure, uremia, respiratory failure, hemophilia, Wilson's disease, etc.

About Shanghai Jiao Tong University School Of Medicine

Shanghai Jiao Tong University School of Medicine is a leading academic institution in China, renowned for its commitment to advancing medical research and education. As a prominent clinical trial sponsor, the school leverages its extensive expertise in biomedical sciences and innovative healthcare solutions to conduct rigorous clinical studies aimed at improving patient outcomes. With a focus on collaboration and translational research, the institution fosters partnerships with healthcare providers, industry leaders, and regulatory bodies to ensure the highest standards of scientific integrity and ethical conduct in clinical trials. Through its research initiatives, Shanghai Jiao Tong University School of Medicine strives to contribute significantly to the global medical community and enhance the quality of healthcare delivery.

Locations

Xiamen, Fujian, China

Baotou, Inner Mongolia, China

Dalian, Liaoning, China

Xuchang, Henan, China

Shanghai, Shanghai, China

Wuhan, Hubei, China

Luoyang, Henan, China

Shanghai, Shanghai, China

Chongqing, Chongqing, China

Dalian, Liaoning, China

Chongqing, Chongqing, China

Wuwei, Gansu, China

Qinzhou, Guangxi, China

Shanghai, Shanghai, China

Chengdu, Sichuan, China

Kashgar, Xinjiang, China

Kunming, Yunnan, China

Ningbo, Zhejiang, China

Ningbo, Zhejiang, China

Chongqing, Chongqing, China

Shangqiu, Henan, China

Dalian, Shandong, China

Shanghai, Shanghai, China

Shanghai, Shanghai, China

Tianjing, Tianjing, China

Shaoxing, Zhejiang, China

Shanghai, Shanghai, China

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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